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PREFERRED TERM

HYDROGEN-DEUTERIUM OXIDE  

DEFINITION

  • Deuterium Oxide is a stable, non-radioactive isotopic form of water, containing 2 atoms of deuterium (D) and one atom of oxygen (2D2O), with DNA-labeling activity. Upon ingestion of deuterium oxide, 2H is incorporated into the deoxyribose moiety of DNA of newly divided cells. Rapidly dividing cells, as in the case of B-cell chronic lymphocytic leukemia (B-CLL), can be labeled with deuterium oxide and measured using gas chromatography and/or mass spectrometry.

BROADER CONCEPT

CHANGE NOTE

  • 2020-10-16 11:48:19.0 [sritz] Insert Concept add broader relation (Hydrogen-Deuterium Oxide [f259ddd3-87d3-4a2f-b39d-ed3cce629f3d,560736] - HYDROGEN COMPOUNDS [d8dcfd36-f71c-499f-84f5-43da9fee26c5,553197]);
  • 2020-10-16 11:51:55.0 [sritz] Rename Concept update PrefLabel (HYDROGEN-DEUTERIUM OXIDE);
  • 2020-10-16 11:59:13.0 [sritz] insert Definition (id: null text: Deuterium Oxide is a stable, non-radioactive isotopic form of water, containing 2 atoms of deuterium (D) and one atom of oxygen (2D2O), with DNA-labeling activity. Upon ingestion of deuterium oxide, 2H is incorporated into the deoxyribose moiety of DNA of newly divided cells. Rapidly dividing cells, as in the case of B-cell chronic lymphocytic leukemia (B-CLL), can be labeled with deuterium oxide and measured using gas chromatography and/or mass spectrometry. language code: en);

URI

https://gcmd.earthdata.nasa.gov/kms/concept/f259ddd3-87d3-4a2f-b39d-ed3cce629f3d

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